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Bioinformatic analysis of the neprilysin (M13) family of peptidases reveals complex evolutionary and functional relationships
BACKGROUND: The neprilysin (M13) family of endopeptidases are zinc-metalloenzymes, the majority of which are type II integral membrane proteins. The best characterised of this family is neprilysin, which has important roles in inactivating signalling peptides involved in modulating neuronal activity...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259306/ https://www.ncbi.nlm.nih.gov/pubmed/18215274 http://dx.doi.org/10.1186/1471-2148-8-16 |