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Association of TRAF2 with the short form of cellular FLICE-like inhibitory protein prevents TNFR1-mediated apoptosis

BACKGROUND: We have previously shown that c-FLIP(L )is a more potent inhibitor than c-FLIP(S )of Fas ligand-induced apoptosis and that c-FLIP(L )physically binds to Daxx, an alternative Fas-signaling adaptor. Here we examined whether c-FLIP(S )effectively inhibits TNFR1-mediated apoptosis and trigge...

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Detalles Bibliográficos
Autores principales: Kim, Dong-Joon, Park, Chan, Oh, Bermseok, Kim, Young-Youl
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259347/
https://www.ncbi.nlm.nih.gov/pubmed/18190721
http://dx.doi.org/10.1186/1750-2187-3-2