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Design of a trans protease lentiviral packaging system that produces high titer virus
BACKGROUND: The structural and enzymatic proteins of the human immunodeficiency virus (HIV) are initially generated as two long polyproteins encoded from overlapping reading frames, one producing the structural proteins (Gag) and the second producing both structural and enzymatic proteins (Gag-Pol)....
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259377/ https://www.ncbi.nlm.nih.gov/pubmed/18163907 http://dx.doi.org/10.1186/1742-4690-4-96 |