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Design of a trans protease lentiviral packaging system that produces high titer virus

BACKGROUND: The structural and enzymatic proteins of the human immunodeficiency virus (HIV) are initially generated as two long polyproteins encoded from overlapping reading frames, one producing the structural proteins (Gag) and the second producing both structural and enzymatic proteins (Gag-Pol)....

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Detalles Bibliográficos
Autores principales: Westerman, Karen A, Ao, Zhujun, Cohen, Éric A, Leboulch, Philippe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259377/
https://www.ncbi.nlm.nih.gov/pubmed/18163907
http://dx.doi.org/10.1186/1742-4690-4-96