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Modeling Escherichia coli signal peptidase complex with bound substrate: determinants in the mature peptide influencing signal peptide cleavage

BACKGROUND: Type I signal peptidases (SPases) are essential membrane-bound serine proteases responsible for the cleavage of signal peptides from proteins that are translocated across biological membranes. The crystal structure of SPase in complex with signal peptide has not been solved and their sub...

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Detalles Bibliográficos
Autores principales: Choo, Khar Heng, Tong, Joo Chuan, Ranganathan, Shoba
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259416/
https://www.ncbi.nlm.nih.gov/pubmed/18315846
http://dx.doi.org/10.1186/1471-2105-9-S1-S15