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Identification of human-to-human transmissibility factors in PB2 proteins of influenza A by large-scale mutual information analysis
BACKGROUND: The identification of mutations that confer unique properties to a pathogen, such as host range, is of fundamental importance in the fight against disease. This paper describes a novel method for identifying amino acid sites that distinguish specific sets of protein sequences, by compara...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259419/ https://www.ncbi.nlm.nih.gov/pubmed/18315849 http://dx.doi.org/10.1186/1471-2105-9-S1-S18 |