The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

Mutations in the gene autoimmune regulator (AIRE) cause autoimmune polyendocrinopathy candidiasis ectodermal dystrophy. AIRE is expressed in thymic medullary epithelial cells, where it promotes the expression of tissue-restricted antigens. By the combined use of biochemical and biophysical methods,...

Descripción completa

Detalles Bibliográficos
Autores principales: Org, Tõnis, Chignola, Francesca, Hetényi, Csaba, Gaetani, Massimiliano, Rebane, Ana, Liiv, Ingrid, Maran, Uko, Mollica, Luca, Bottomley, Matthew J, Musco, Giovanna, Peterson, Pärt
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Scientific Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2261226/
https://www.ncbi.nlm.nih.gov/pubmed/18292755
http://dx.doi.org/10.1038/embor.2008.11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2261226/
https://www.ncbi.nlm.nih.gov/pubmed/18292755
http://dx.doi.org/10.1038/embor.2008.11

Ejemplares similares