Dicholine salt of succinic acid, a neuronal insulin sensitizer, ameliorates cognitive deficits in rodent models of normal aging, chronic cerebral hypoperfusion, and beta-amyloid peptide-(25–35)-induced amnesia

BACKGROUND: Accumulated evidence suggests that insulin resistance and impairments in cerebral insulin receptor signaling may contribute to age-related cognitive deficits and Alzheimer's disease. The enhancement of insulin receptor signaling is, therefore, a promising strategy for the treatment...

Descripción completa

Detalles Bibliográficos
Autores principales: Storozheva, Zinaida I, Proshin, Andrey T, Sherstnev, Vladimir V, Storozhevykh, Tatiana P, Senilova, Yana E, Persiyantseva, Nadezhda A, Pinelis, Vsevolod G, Semenova, Natalia A, Zakharova, Elena I, Pomytkin, Igor A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2262060/
https://www.ncbi.nlm.nih.gov/pubmed/18215309
http://dx.doi.org/10.1186/1471-2210-8-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2262060/
https://www.ncbi.nlm.nih.gov/pubmed/18215309
http://dx.doi.org/10.1186/1471-2210-8-1

Ejemplares similares