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Mutational analysis of βCOP (Sec26p) identifies an appendage domain critical for function

BACKGROUND: The appendage domain of the γCOP subunit of the COPI vesicle coat bears a striking structural resemblance to adaptin-family appendages despite limited primary sequence homology. Both the γCOP appendage domain and an equivalent region on βCOP contain the FxxxW motif; the conservation of t...

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Detalles Bibliográficos
Autores principales: DeRegis, Carol J, Rahl, Peter B, Hoffman, Gregory R, Cerione, Richard A, Collins, Ruth N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2262067/
https://www.ncbi.nlm.nih.gov/pubmed/18211691
http://dx.doi.org/10.1186/1471-2121-9-3