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Mutational analysis of βCOP (Sec26p) identifies an appendage domain critical for function
BACKGROUND: The appendage domain of the γCOP subunit of the COPI vesicle coat bears a striking structural resemblance to adaptin-family appendages despite limited primary sequence homology. Both the γCOP appendage domain and an equivalent region on βCOP contain the FxxxW motif; the conservation of t...
Autores principales: | DeRegis, Carol J, Rahl, Peter B, Hoffman, Gregory R, Cerione, Richard A, Collins, Ruth N |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2262067/ https://www.ncbi.nlm.nih.gov/pubmed/18211691 http://dx.doi.org/10.1186/1471-2121-9-3 |
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