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The Impact of the Human DNA Topoisomerase II C-Terminal Domain on Activity
BACKGROUND: Type II DNA topoisomerases (topos) are essential enzymes needed for the resolution of topological problems that occur during DNA metabolic processes. Topos carry out an ATP-dependent strand passage reaction whereby one double helix is passed through a transient break in another. Humans h...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2262138/ https://www.ncbi.nlm.nih.gov/pubmed/18335031 http://dx.doi.org/10.1371/journal.pone.0001754 |