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Strong negative self regulation of Prokaryotic transcription factors increases the intrinsic noise of protein expression

BACKGROUND: Many prokaryotic transcription factors repress their own transcription. It is often asserted that such regulation enables a cell to homeostatically maintain protein abundance. We explore the role of negative self regulation of transcription in regulating the variability of protein abunda...

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Detalles Bibliográficos
Autores principales: Stekel, Dov J, Jenkins, Dafyd J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263017/
https://www.ncbi.nlm.nih.gov/pubmed/18205926
http://dx.doi.org/10.1186/1752-0509-2-6