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Cerebrospinal fluid matrix metalloproteinase-9 increases during treatment of recurrent malignant gliomas

BACKGROUND: Matrix metalloproteinases (MMPs) are enzymes that promote tumor invasion and angiogenesis by enzymatically remodeling the extracellular matrix. MMP-2 and MMP-9 are the most abundant forms of MMPs in malignant gliomas, while a 130 kDa MMP is thought to be MMP-9 complexed to other proteina...

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Detalles Bibliográficos
Autores principales: Wong, Eric T, Alsop, David, Lee, Diana, Tam, Angela, Barron, Loretta, Bloom, Julianne, Gautam, Shiva, Wu, Julian K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263020/
https://www.ncbi.nlm.nih.gov/pubmed/18186943
http://dx.doi.org/10.1186/1743-8454-5-1