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Cerebrospinal fluid matrix metalloproteinase-9 increases during treatment of recurrent malignant gliomas
BACKGROUND: Matrix metalloproteinases (MMPs) are enzymes that promote tumor invasion and angiogenesis by enzymatically remodeling the extracellular matrix. MMP-2 and MMP-9 are the most abundant forms of MMPs in malignant gliomas, while a 130 kDa MMP is thought to be MMP-9 complexed to other proteina...
Autores principales: | Wong, Eric T, Alsop, David, Lee, Diana, Tam, Angela, Barron, Loretta, Bloom, Julianne, Gautam, Shiva, Wu, Julian K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263020/ https://www.ncbi.nlm.nih.gov/pubmed/18186943 http://dx.doi.org/10.1186/1743-8454-5-1 |
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