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Evolutionary Pareto-optimization of stably folding peptides

BACKGROUND: As a rule, peptides are more flexible and unstructured than proteins with their substantial stabilizing hydrophobic cores. Nevertheless, a few stably folding peptides have been discovered. This raises the question whether there may be more such peptides that are unknown as yet. These mol...

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Detalles Bibliográficos
Autores principales: Gronwald, Wolfram, Hohm, Tim, Hoffmann, Daniel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263021/
https://www.ncbi.nlm.nih.gov/pubmed/18284690
http://dx.doi.org/10.1186/1471-2105-9-109