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Enhancing the prediction of protein pairings between interacting families using orthology information

BACKGROUND: It has repeatedly been shown that interacting protein families tend to have similar phylogenetic trees. These similarities can be used to predicting the mapping between two families of interacting proteins (i.e. which proteins from one family interact with which members of the other). Th...

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Detalles Bibliográficos
Autores principales: Izarzugaza, Jose MG, Juan, David, Pons, Carles, Pazos, Florencio, Valencia, Alfonso
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263026/
https://www.ncbi.nlm.nih.gov/pubmed/18215279
http://dx.doi.org/10.1186/1471-2105-9-35