FGF10 maintains distal lung bud epithelium and excessive signaling leads to progenitor state arrest, distalization, and goblet cell metaplasia

BACKGROUND: Interaction with the surrounding mesenchyme is necessary for development of endodermal organs, and Fibroblast growth factors have recently emerged as mesenchymal-expressed morphogens that direct endodermal morphogenesis. The fibroblast growth factor 10 (Fgf10) null mouse is characterized...

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Detalles Bibliográficos
Autores principales: Nyeng, Pia, Norgaard, Gitte A, Kobberup, Sune, Jensen, Jan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263027/
https://www.ncbi.nlm.nih.gov/pubmed/18186922
http://dx.doi.org/10.1186/1471-213X-8-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263027/
https://www.ncbi.nlm.nih.gov/pubmed/18186922
http://dx.doi.org/10.1186/1471-213X-8-2

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