hMMS2 serves a redundant role in human PCNA polyubiquitination

BACKGROUND: In yeast, DNA damage leads to the mono and polyubiquitination of the sliding clamp PCNA. Monoubiquitination of PCNA is controlled by RAD18 (E3 ligase) and RAD6 (E2 conjugating enzyme), while the extension of the monoubiquitinated PCNA into a polyubiquitinated substrate is governed by RAD...

Descripción completa

Detalles Bibliográficos
Autores principales: Brun, Jan, Chiu, Roland, Lockhart, Katherine, Xiao, Wei, Wouters, Bradly G, Gray, Douglas A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263069/
https://www.ncbi.nlm.nih.gov/pubmed/18284681
http://dx.doi.org/10.1186/1471-2199-9-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263069/
https://www.ncbi.nlm.nih.gov/pubmed/18284681
http://dx.doi.org/10.1186/1471-2199-9-24

Ejemplares similares