Reduced body weight is a common effect of gene knockout in mice

BACKGROUND: During a search for obesity candidate genes in a small region of the mouse genome, we noticed that many genes when knocked out influence body weight. To determine whether this was a general feature of gene knockout or a chance occurrence, we surveyed the Jackson Laboratory Mouse Genome D...

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Detalles Bibliográficos
Autores principales: Reed, Danielle R, Lawler, Maureen P, Tordoff, Michael G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263071/
https://www.ncbi.nlm.nih.gov/pubmed/18182103
http://dx.doi.org/10.1186/1471-2156-9-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263071/
https://www.ncbi.nlm.nih.gov/pubmed/18182103
http://dx.doi.org/10.1186/1471-2156-9-4

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