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Reduced body weight is a common effect of gene knockout in mice
BACKGROUND: During a search for obesity candidate genes in a small region of the mouse genome, we noticed that many genes when knocked out influence body weight. To determine whether this was a general feature of gene knockout or a chance occurrence, we surveyed the Jackson Laboratory Mouse Genome D...
Autores principales: | Reed, Danielle R, Lawler, Maureen P, Tordoff, Michael G |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263071/ https://www.ncbi.nlm.nih.gov/pubmed/18182103 http://dx.doi.org/10.1186/1471-2156-9-4 |
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