Amino Acid Similarity Accounts for T Cell Cross-Reactivity and for “Holes” in the T Cell Repertoire

BACKGROUND: Cytotoxic T cell (CTL) cross-reactivity is believed to play a pivotal role in generating immune responses but the extent and mechanisms of CTL cross-reactivity remain largely unknown. Several studies suggest that CTL clones can recognize highly diverse peptides, some sharing no obvious s...

Descripción completa

Detalles Bibliográficos
Autores principales: Frankild, Sune, de Boer, Rob J., Lund, Ole, Nielsen, Morten, Kesmir, Can
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263130/
https://www.ncbi.nlm.nih.gov/pubmed/18350167
http://dx.doi.org/10.1371/journal.pone.0001831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263130/
https://www.ncbi.nlm.nih.gov/pubmed/18350167
http://dx.doi.org/10.1371/journal.pone.0001831

Ejemplares similares