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Low Phytoestrogen Levels in Feed Increase Fetal Serum Estradiol Resulting in the “Fetal Estrogenization Syndrome” and Obesity in CD-1 Mice

BACKGROUND: Although estrogenic chemicals can disrupt development of the reproductive system, there is debate about whether phytoestrogens in soy are beneficial, benign, or harmful. OBJECTIVES: We compared reproductive and metabolic characteristics in male and female mice reared and maintained on no...

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Detalles Bibliográficos
Autores principales: Ruhlen, Rachel L., Howdeshell, Kembra L., Mao, Jiude, Taylor, Julia A., Bronson, Franklin H., Newbold, Retha R., Welshons, Wade V., vom Saal, Frederick S.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265041/
https://www.ncbi.nlm.nih.gov/pubmed/18335098
http://dx.doi.org/10.1289/ehp.10448