Plx1 is required for chromosomal DNA replication under stressful conditions

Polo-like kinase (Plk)1 is required for mitosis progression. However, although Plk1 is expressed throughout the cell cycle, its function during S-phase is unknown. Using Xenopus laevis egg extracts, we demonstrate that Plx1, the Xenopus orthologue of Plk1, is required for DNA replication in the pres...

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Detalles Bibliográficos
Autores principales: Trenz, Kristina, Errico, Alessia, Costanzo, Vincenzo
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265110/
https://www.ncbi.nlm.nih.gov/pubmed/18309293
http://dx.doi.org/10.1038/emboj.2008.29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265110/
https://www.ncbi.nlm.nih.gov/pubmed/18309293
http://dx.doi.org/10.1038/emboj.2008.29

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