Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome

BACKGROUND: Cullin-RING ubiquitin E3 ligases (CRLs) are regulated by modification of an ubiquitin-like protein, Nedd8 (also known as Rub1) on the cullin subunit. Neddylation is shown to facilitate E3 complex assembly; while un-neddylated cullins are bound by CAND1 that prevents recruitment of the su...

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Detalles Bibliográficos
Autores principales: Menon, Suchithra, Tsuge, Tomohiko, Dohmae, Naoshi, Takio, Koji, Wei, Ning
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265268/
https://www.ncbi.nlm.nih.gov/pubmed/18173839
http://dx.doi.org/10.1186/1471-2091-9-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265268/
https://www.ncbi.nlm.nih.gov/pubmed/18173839
http://dx.doi.org/10.1186/1471-2091-9-1

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