Multiple independent origins of a protease inhibitor resistance mutation in salvage therapy patients

BACKGROUND: Combination anti-viral therapies have reduced treatment failure rates by requiring multiple specific mutations to be selected on the same viral genome to impart high-level drug resistance. To determine if the common protease inhibitor resistance mutation L90M is only selected once or rep...

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Detalles Bibliográficos
Autores principales: Kapoor, Amit, Shapiro, Beth, Shafer, Robert W, Shulman, Nancy, Rhee, Soo-Yon, Delwart, Eric L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265302/
https://www.ncbi.nlm.nih.gov/pubmed/18221530
http://dx.doi.org/10.1186/1742-4690-5-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265302/
https://www.ncbi.nlm.nih.gov/pubmed/18221530
http://dx.doi.org/10.1186/1742-4690-5-7

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