Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion

Invasive cancer cells form dynamic adhesive structures associated with matrix degradation called invadopodia. Calpain 2 is a calcium-dependent intracellular protease that regulates adhesion turnover and disassembly through the targeting of specific substrates such as talin. Here, we describe a novel...

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Detalles Bibliográficos
Autores principales: Cortesio, Christa L., Chan, Keefe T., Perrin, Benjamin J., Burton, Nicholas O., Zhang, Sheng, Zhang, Zhong-Yin, Huttenlocher, Anna
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265405/
https://www.ncbi.nlm.nih.gov/pubmed/18332219
http://dx.doi.org/10.1083/jcb.200708048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265405/
https://www.ncbi.nlm.nih.gov/pubmed/18332219
http://dx.doi.org/10.1083/jcb.200708048

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