Integrin-linked kinase stabilizes myotendinous junctions and protects muscle from stress-induced damage

Skeletal muscle expresses high levels of integrin-linked kinase (ILK), predominantly at myotendinous junctions (MTJs) and costameres. ILK binds the cytoplasmic domain of β1 integrin and mediates phosphorylation of protein kinase B (PKB)/Akt, which in turn plays a central role during skeletal muscle...

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Detalles Bibliográficos
Autores principales: Wang, Hao-Ven, Chang, Ling-Wei, Brixius, Klara, Wickström, Sara A., Montanez, Eloi, Thievessen, Ingo, Schwander, Martin, Müller, Ulrich, Bloch, Wilhelm, Mayer, Ulrike, Fässler, Reinhard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265410/
https://www.ncbi.nlm.nih.gov/pubmed/18332223
http://dx.doi.org/10.1083/jcb.200707175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265410/
https://www.ncbi.nlm.nih.gov/pubmed/18332223
http://dx.doi.org/10.1083/jcb.200707175

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