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Integrin-linked kinase stabilizes myotendinous junctions and protects muscle from stress-induced damage
Skeletal muscle expresses high levels of integrin-linked kinase (ILK), predominantly at myotendinous junctions (MTJs) and costameres. ILK binds the cytoplasmic domain of β1 integrin and mediates phosphorylation of protein kinase B (PKB)/Akt, which in turn plays a central role during skeletal muscle...
Autores principales: | Wang, Hao-Ven, Chang, Ling-Wei, Brixius, Klara, Wickström, Sara A., Montanez, Eloi, Thievessen, Ingo, Schwander, Martin, Müller, Ulrich, Bloch, Wilhelm, Mayer, Ulrike, Fässler, Reinhard |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265410/ https://www.ncbi.nlm.nih.gov/pubmed/18332223 http://dx.doi.org/10.1083/jcb.200707175 |
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