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A Hidden Feedback in Signaling Cascades Is Revealed

Cycles involving covalent modification of proteins are key components of the intracellular signaling machinery. Each cycle is comprised of two interconvertable forms of a particular protein. A classic signaling pathway is structured by a chain or cascade of basic cycle units in such a way that the a...

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Detalles Bibliográficos
Autores principales: Ventura, Alejandra C., Sepulchre, Jacques-A., Merajver, Sofía D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265423/
https://www.ncbi.nlm.nih.gov/pubmed/18369431
http://dx.doi.org/10.1371/journal.pcbi.1000041