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Cationic Amino Acid Transporter-2 Regulates Immunity by Modulating Arginase Activity

Cationic amino acid transporters (CAT) are important regulators of NOS2 and ARG1 activity because they regulate L-arginine availability. However, their role in the development of Th1/Th2 effector functions following infection has not been investigated. Here we dissect the function of CAT2 by studyin...

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Detalles Bibliográficos
Autores principales: Thompson, Robert W., Pesce, John T., Ramalingam, Thirumalai, Wilson, Mark S., White, Sandy, Cheever, Allen W., Ricklefs, Stacy M., Porcella, Stephen F., Li, Lili, Ellies, Lesley G., Wynn, Thomas A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265428/
https://www.ncbi.nlm.nih.gov/pubmed/18369473
http://dx.doi.org/10.1371/journal.ppat.1000023