Effective transcription factor binding site prediction using a combination of optimization, a genetic algorithm and discriminant analysis to capture distant interactions

BACKGROUND: Reliable transcription factor binding site (TFBS) prediction methods are essential for computer annotation of large amount of genome sequence data. However, current methods to predict TFBSs are hampered by the high false-positive rates that occur when only sequence conservation at the co...

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Detalles Bibliográficos
Autores principales: Levitsky, Victor G, Ignatieva, Elena V, Ananko, Elena A, Turnaev, Igor I, Merkulova, Tatyana I, Kolchanov, Nikolay A, Hodgman, TC
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265442/
https://www.ncbi.nlm.nih.gov/pubmed/18093302
http://dx.doi.org/10.1186/1471-2105-8-481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265442/
https://www.ncbi.nlm.nih.gov/pubmed/18093302
http://dx.doi.org/10.1186/1471-2105-8-481

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