Multi-Scale Simulations Provide Supporting Evidence for the Hypothesis of Intramolecular Protein Translocation in GroEL/GroES Complexes

The biological function of chaperone complexes is to assist the folding of non-native proteins. The widely studied GroEL chaperonin is a double-barreled complex that can trap non-native proteins in one of its two barrels. The ATP-driven binding of a GroES cap then results in a major structural chang...

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Detalles Bibliográficos
Autores principales: Coluzza, Ivan, De Simone, Alfonso, Fraternali, Franca, Frenkel, Daan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265519/
https://www.ncbi.nlm.nih.gov/pubmed/18463703
http://dx.doi.org/10.1371/journal.pcbi.1000006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265519/
https://www.ncbi.nlm.nih.gov/pubmed/18463703
http://dx.doi.org/10.1371/journal.pcbi.1000006

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