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Evolution of a Core Gene Network for Skeletogenesis in Chordates

The skeleton is one of the most important features for the reconstruction of vertebrate phylogeny but few data are available to understand its molecular origin. In mammals the Runt genes are central regulators of skeletogenesis. Runx2 was shown to be essential for osteoblast differentiation, tooth d...

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Detalles Bibliográficos
Autores principales: Hecht, Jochen, Stricker, Sigmar, Wiecha, Ulrike, Stiege, Asita, Panopoulou, Georgia, Podsiadlowski, Lars, Poustka, Albert J., Dieterich, Christoph, Ehrich, Siegfried, Suvorova, Julia, Mundlos, Stefan, Seitz, Volkhard
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265531/
https://www.ncbi.nlm.nih.gov/pubmed/18369444
http://dx.doi.org/10.1371/journal.pgen.1000025