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Evolution of a Core Gene Network for Skeletogenesis in Chordates
The skeleton is one of the most important features for the reconstruction of vertebrate phylogeny but few data are available to understand its molecular origin. In mammals the Runt genes are central regulators of skeletogenesis. Runx2 was shown to be essential for osteoblast differentiation, tooth d...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265531/ https://www.ncbi.nlm.nih.gov/pubmed/18369444 http://dx.doi.org/10.1371/journal.pgen.1000025 |