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Structural Elements Regulating Amyloidogenesis: A Cholinesterase Model System

Polymerization into amyloid fibrils is a crucial step in the pathogenesis of neurodegenerative syndromes. Amyloid assembly is governed by properties of the sequence backbone and specific side-chain interactions, since fibrils from unrelated sequences possess similar structures and morphologies. Ther...

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Detalles Bibliográficos
Autores principales: Jean, Létitia, Lee, Chiu Fan, Shaw, Michael, Vaux, David J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265548/
https://www.ncbi.nlm.nih.gov/pubmed/18350169
http://dx.doi.org/10.1371/journal.pone.0001834