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Structural Elements Regulating Amyloidogenesis: A Cholinesterase Model System
Polymerization into amyloid fibrils is a crucial step in the pathogenesis of neurodegenerative syndromes. Amyloid assembly is governed by properties of the sequence backbone and specific side-chain interactions, since fibrils from unrelated sequences possess similar structures and morphologies. Ther...
Autores principales: | Jean, Létitia, Lee, Chiu Fan, Shaw, Michael, Vaux, David J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265548/ https://www.ncbi.nlm.nih.gov/pubmed/18350169 http://dx.doi.org/10.1371/journal.pone.0001834 |
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