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Anchor Side Chains of Short Peptide Fragments Trigger Ligand-Exchange of Class II MHC Molecules

Class II MHC molecules display peptides on the cell surface for the surveillance by CD4+ T cells. To ensure that these ligands accurately reflect the content of the intracellular MHC loading compartment, a complex processing pathway has evolved that delivers only stable peptide/MHC complexes to the...

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Detalles Bibliográficos
Autores principales: Gupta, Shashank, Höpner, Sabine, Rupp, Bernd, Günther, Sebastian, Dickhaut, Katharina, Agarwal, Noopur, Cardoso, M. Cristina, Kühne, Ronald, Wiesmüller, Karl-Heinz, Jung, Günther, Falk, Kirsten, Rötzschke, Olaf
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265549/
https://www.ncbi.nlm.nih.gov/pubmed/18350151
http://dx.doi.org/10.1371/journal.pone.0001814