Recruitment to the Nuclear Periphery Can Alter Expression of Genes in Human Cells

The spatial organisation of the genome in the nucleus has a role in the regulation of gene expression. In vertebrates, chromosomal regions with low gene-density are located close to the nuclear periphery. Correlations have also been made between the transcriptional state of some genes and their loca...

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Detalles Bibliográficos
Autores principales: Finlan, Lee E., Sproul, Duncan, Thomson, Inga, Boyle, Shelagh, Kerr, Elizabeth, Perry, Paul, Ylstra, Bauke, Chubb, Jonathan R., Bickmore, Wendy A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265557/
https://www.ncbi.nlm.nih.gov/pubmed/18369458
http://dx.doi.org/10.1371/journal.pgen.1000039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265557/
https://www.ncbi.nlm.nih.gov/pubmed/18369458
http://dx.doi.org/10.1371/journal.pgen.1000039

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