Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis

During meiosis, homologous chromosomes undergo synapsis and recombination. We identify TEX15 as a novel protein that is required for chromosomal synapsis and meiotic recombination. Loss of TEX15 function in mice causes early meiotic arrest in males but not in females. Specifically, TEX15-deficient s...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Fang, Eckardt, Sigrid, Leu, N. Adrian, McLaughlin, K. John, Wang, Peijing Jeremy
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265566/
https://www.ncbi.nlm.nih.gov/pubmed/18283110
http://dx.doi.org/10.1083/jcb.200709057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265566/
https://www.ncbi.nlm.nih.gov/pubmed/18283110
http://dx.doi.org/10.1083/jcb.200709057

Ejemplares similares