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Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis

During meiosis, homologous chromosomes undergo synapsis and recombination. We identify TEX15 as a novel protein that is required for chromosomal synapsis and meiotic recombination. Loss of TEX15 function in mice causes early meiotic arrest in males but not in females. Specifically, TEX15-deficient s...

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Detalles Bibliográficos
Autores principales:	Yang, Fang, Eckardt, Sigrid, Leu, N. Adrian, McLaughlin, K. John, Wang, Peijing Jeremy
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265566/ https://www.ncbi.nlm.nih.gov/pubmed/18283110 http://dx.doi.org/10.1083/jcb.200709057

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