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Examining the link between chromosomal instability and aneuploidy in human cells

Solid tumors can be highly aneuploid and many display high rates of chromosome missegregation in a phenomenon called chromosomal instability (CIN). In principle, aneuploidy is the consequence of CIN, but the relationship between CIN and aneuploidy has not been clearly defined. In this study, we use...

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Detalles Bibliográficos
Autores principales: Thompson, Sarah L., Compton, Duane A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265570/
https://www.ncbi.nlm.nih.gov/pubmed/18283116
http://dx.doi.org/10.1083/jcb.200712029