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Endosomal entry regulates Notch receptor activation in Drosophila melanogaster

Signaling through the transmembrane receptor Notch is widely used throughout animal development and is a major regulator of cell proliferation and differentiation. During canonical Notch signaling, internalization and recycling of Notch ligands controls signaling activity, but the involvement of end...

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Detalles Bibliográficos
Autores principales: Vaccari, Thomas, Lu, Han, Kanwar, Ritu, Fortini, Mark E., Bilder, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265571/
https://www.ncbi.nlm.nih.gov/pubmed/18299346
http://dx.doi.org/10.1083/jcb.200708127