FOXO-regulated transcription restricts overgrowth of Tsc mutant organs

FOXO is thought to function as a repressor of growth that is, in turn, inhibited by insulin signaling. However, inactivating mutations in Drosophila melanogaster FOXO result in viable flies of normal size, which raises a question over the involvement of FOXO in growth regulation. Previously, a growt...

Descripción completa

Detalles Bibliográficos
Autores principales: Harvey, Kieran F., Mattila, Jaakko, Sofer, Avi, Bennett, F. Christian, Ramsey, Matthew R., Ellisen, Leif W., Puig, Oscar, Hariharan, Iswar K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265581/
https://www.ncbi.nlm.nih.gov/pubmed/18299344
http://dx.doi.org/10.1083/jcb.200710100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265581/
https://www.ncbi.nlm.nih.gov/pubmed/18299344
http://dx.doi.org/10.1083/jcb.200710100

Ejemplares similares