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Retinoic acid decreases ATF-2 phosphorylation and sensitizes melanoma cells to taxol-mediated growth inhibition

Cutaneous melanoma is often resistant to chemo- and radiotherapy. This resistance has recently been demonstrated to be due, at least in part, to high activating transcription factor 2 (ATF-2) activity in these tumors. In concordance with these reports, we found that B16 mouse melanoma cells had high...

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Detalles Bibliográficos
Autores principales: Huang, Ying, Minigh, Jennifer, Miles, Sarah, Niles, Richard M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265711/
https://www.ncbi.nlm.nih.gov/pubmed/18269766
http://dx.doi.org/10.1186/1750-2187-3-3