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Alteration of viral lipid composition by expression of the phospholipid floppase ABCB4 reduces HIV vector infectivity

BACKGROUND: The presence of cholesterol in the Human Immunodeficiency Virus (HIV) lipid envelop is important for viral function as cholesterol depleted viral particles show reduced infectivity. However, it is less well established whether other viral membrane lipids are also important for HIV infect...

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Detalles Bibliográficos
Autores principales: van Til, Niek P, Heutinck, Kirstin M, van der Rijt, Roos, Paulusma, Coen C, van Wijland, Michel, Markusic, David M, Elferink, Ronald PJ Oude, Seppen, Jurgen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265746/
https://www.ncbi.nlm.nih.gov/pubmed/18241333
http://dx.doi.org/10.1186/1742-4690-5-14