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Alteration of viral lipid composition by expression of the phospholipid floppase ABCB4 reduces HIV vector infectivity
BACKGROUND: The presence of cholesterol in the Human Immunodeficiency Virus (HIV) lipid envelop is important for viral function as cholesterol depleted viral particles show reduced infectivity. However, it is less well established whether other viral membrane lipids are also important for HIV infect...
Autores principales: | van Til, Niek P, Heutinck, Kirstin M, van der Rijt, Roos, Paulusma, Coen C, van Wijland, Michel, Markusic, David M, Elferink, Ronald PJ Oude, Seppen, Jurgen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265746/ https://www.ncbi.nlm.nih.gov/pubmed/18241333 http://dx.doi.org/10.1186/1742-4690-5-14 |
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