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K Channel Subconductance Levels Result from Heteromeric Pore Conformations
Voltage-gated K channels assemble from four identical subunits symmetrically arranged around a central permeation pathway. Each subunit harbors a voltage-sensing domain. The sigmoidal nature of the activation kinetics suggests that multiple sensors need to undergo a conformational change before the...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266570/ https://www.ncbi.nlm.nih.gov/pubmed/16043772 http://dx.doi.org/10.1085/jgp.200509253 |