Phospholipase C in Living Cells: Activation, Inhibition, Ca(2+) Requirement, and Regulation of M Current

We have further tested the hypothesis that receptor-mediated modulation of KCNQ channels involves depletion of phosphatidylinositol 4,5-bisphosphate (PIP(2)) by phosphoinositide-specific phospholipase C (PLC). We used four parallel assays to characterize the agonist-induced PLC response of cells (ts...

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Detalles Bibliográficos
Autores principales: Horowitz, Lisa F., Hirdes, Wiebke, Suh, Byung-Chang, Hilgemann, Donald W., Mackie, Ken, Hille, Bertil
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266577/
https://www.ncbi.nlm.nih.gov/pubmed/16129772
http://dx.doi.org/10.1085/jgp.200509309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266577/
https://www.ncbi.nlm.nih.gov/pubmed/16129772
http://dx.doi.org/10.1085/jgp.200509309

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