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Phospholipase C in Living Cells: Activation, Inhibition, Ca(2+) Requirement, and Regulation of M Current

We have further tested the hypothesis that receptor-mediated modulation of KCNQ channels involves depletion of phosphatidylinositol 4,5-bisphosphate (PIP(2)) by phosphoinositide-specific phospholipase C (PLC). We used four parallel assays to characterize the agonist-induced PLC response of cells (ts...

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Detalles Bibliográficos
Autores principales:	Horowitz, Lisa F., Hirdes, Wiebke, Suh, Byung-Chang, Hilgemann, Donald W., Mackie, Ken, Hille, Bertil
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266577/ https://www.ncbi.nlm.nih.gov/pubmed/16129772 http://dx.doi.org/10.1085/jgp.200509309

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