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Functional Architecture of the Inner Pore of a Voltage-gated Ca(2+) Channel

The inner pore of voltage-gated Ca(2+) channels (VGCCs) is functionally important, but little is known about the architecture of this region. In K(+) channels, this part of the pore is formed by the S6/M2 transmembrane segments from four symmetrically arranged subunits. The Ca(2+) channel pore, howe...

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Detalles Bibliográficos
Autores principales: Zhen, Xiao-guang, Xie, Cheng, Fitzmaurice, Aileen, Schoonover, Carl E., Orenstein, Eleza T., Yang, Jian
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266581/
https://www.ncbi.nlm.nih.gov/pubmed/16129770
http://dx.doi.org/10.1085/jgp.200509292