Functional Role and Affinity of Inorganic Cations in Stabilizing the Tetrameric Structure of the KcsA K(+) Channel

Crystal structures of the tetrameric KcsA K(+) channel reveal seven distinct binding sites for K(+) ions within the central pore formed at the fourfold rotational symmetry axis. Coordination of an individual K(+) ion by eight protein oxygen atoms within the selectivity filter suggests that ion-subun...

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Detalles Bibliográficos
Autores principales: Krishnan, Manoj N., Bingham, Jon-Paul, Lee, Siew Hwee, Trombley, Patrick, Moczydlowski, Edward
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266582/
https://www.ncbi.nlm.nih.gov/pubmed/16129774
http://dx.doi.org/10.1085/jgp.200509323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266582/
https://www.ncbi.nlm.nih.gov/pubmed/16129774
http://dx.doi.org/10.1085/jgp.200509323

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